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Studies have identified that autophagy deficiency leads to NRF2 activation due to p62 accumulation [83]
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Antioxidant complex - vitamin E, coenzyme Q10 and alpha-lipoic acid
S., Puhan, M
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Additionally, findings revealed that grape seed extract inhibited the phosphorylation of proteins such as ERK, JNK, and P38 in human epidermal keratinocytes subjected to UVB irradiation, suggesting its ability to suppress the MAPK signaling pathway and consequently reduce UVB-induced collagen degradation (60, 76)
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